N-Methyltyramine

N-Methyltyramine

0N-Methyltyramine (also known as NMT) is a natural phenethylamine compound found in a variety of plants. It is often used in dietary supplements for its potential benefits, although its effectiveness and safety are not fully understood.

History

N-Methyltyramine was first isolated from barley in the early 20th century. It has since been found in a variety of other plants, including bitter orange, Acacia berlandieri, and Acacia rigidula.

Structure and Properties

N-Methyltyramine is a phenethylamine derivative, meaning it has a phenyl ring connected to an amino (NH2) group through a two-carbon chain. The 'N-Methyl' part of its name refers to the addition of a methyl group to the nitrogen atom of the amino group.

Biological Activity

N-Methyltyramine is believed to act as a monoamine releasing agent, specifically for norepinephrine and dopamine. This means it may increase the levels of these neurotransmitters in the brain, which could potentially lead to increased alertness, focus, and energy levels.

Uses and Potential Benefits

N-Methyltyramine is often included in dietary supplements, particularly those marketed for weight loss and athletic performance enhancement. It is believed to stimulate the release of norepinephrine, which can increase heart rate and blood pressure, potentially leading to increased calorie burning and improved athletic performance.

Safety and Side Effects

The safety of N-Methyltyramine is not fully understood. Some studies suggest it may increase heart rate and blood pressure, which could potentially lead to adverse cardiovascular events in some individuals. It is recommended that individuals with pre-existing heart conditions or high blood pressure avoid products containing N-Methyltyramine.

See Also

• Phenethylamine
• Norepinephrine
• Dopamine
• Dietary Supplements

References

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