NEFA

NEFA or Non-Esterified Fatty Acids are types of fatty acids that are not attached to other molecules, hence the term "non-esterified". They are also known as free fatty acids (FFA). NEFA plays a crucial role in the body's metabolic processes, particularly in lipid metabolism and energy production.

Overview[edit | edit source]

NEFA are released from adipose tissue (fat cells) into the bloodstream and transported to various tissues, including the liver, muscles, and heart, where they are used as a source of energy. The concentration of NEFA in the blood can be influenced by several factors, including diet, physical activity, and hormonal regulation.

Role in Metabolism[edit | edit source]

In the body, NEFA are primarily used for energy production. They are broken down through a process called beta-oxidation to produce adenosine triphosphate (ATP), the body's main energy currency. This process occurs in the mitochondria, the "powerhouse" of the cell.

Health Implications[edit | edit source]

High levels of NEFA in the blood have been associated with several health conditions, including type 2 diabetes, obesity, and cardiovascular disease. This is because excess NEFA can interfere with insulin action, leading to insulin resistance and increased blood sugar levels. They can also accumulate in non-adipose tissues, causing lipotoxicity.

Measurement[edit | edit source]

The concentration of NEFA in the blood can be measured using a blood test. This can provide valuable information about a person's metabolic health and risk of developing certain diseases.

See Also[edit | edit source]

NEFA Resources
Need Help Finding a Doctor? Need help finding a doctor or specialist anywhere in the world? Explore our world directory. WikiMD's DocFinder can assist you in locating millions of physicians.	Medical Knowledge Access the latest research - Most recent articles Ongoing trials.