Narcobarbital

Narcobarbital is a barbiturate derivative that was first synthesized in 1927. It is primarily used as a sedative and hypnotic. Narcobarbital is also known by its trade name, Nembutal.

History

Narcobarbital was first synthesized in 1927 by the German pharmaceutical company Bayer. It was marketed under the trade name Nembutal, which is a contraction of the chemical name N-ethyl-methyl-butyl-al.

Medical Uses

Narcobarbital is primarily used as a sedative and hypnotic. It is also used in the treatment of insomnia and as a pre-anesthetic in surgical procedures.

Pharmacology

Narcobarbital works by increasing the activity of the gamma-aminobutyric acid (GABA) neurotransmitter in the brain. GABA inhibits the activity of the nervous system, which results in sedative and hypnotic effects.

Side Effects

Common side effects of narcobarbital include drowsiness, dizziness, and loss of coordination. More serious side effects can include respiratory depression, addiction, and risk of overdose.

See Also

• Barbiturate
• Sedative
• Hypnotic
• Insomnia
• Gamma-aminobutyric acid

Narcobarbital Resources
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