Nevan Krogan

NevanJKrogan

Nevan Krogan is a Canadian-American molecular biologist and systems biologist known for his work in protein-protein interactions and infectious diseases. He is a professor at the University of California, San Francisco (UCSF) and the director of the Quantitative Biosciences Institute (QBI) at UCSF. Krogan is also a senior investigator at the Gladstone Institutes.

Early Life and Education

Nevan Krogan was born in Canada. He completed his undergraduate studies at the University of Western Ontario, where he earned a Bachelor of Science degree in Biochemistry. He then pursued his Ph.D. in Medical Genetics at the University of Toronto under the supervision of Jack Greenblatt.

Career

After completing his Ph.D., Krogan conducted postdoctoral research at the University of California, San Francisco in the laboratory of Jonathan Weissman. He joined the faculty at UCSF in 2006 and has since become a prominent figure in the field of systems biology.

Krogan's research focuses on understanding the complex interactions between proteins within cells and how these interactions are altered in various diseases, including cancer and infectious diseases. His work has led to significant insights into the molecular mechanisms of diseases and has identified potential targets for therapeutic intervention.

Research Contributions

Nevan Krogan has made numerous contributions to the field of molecular biology and systems biology. Some of his notable research achievements include:

• Mapping the protein-protein interaction networks of various organisms, including Saccharomyces cerevisiae (baker's yeast) and Homo sapiens (humans).
• Investigating the host-pathogen interactions in infectious diseases such as HIV, hepatitis C, and SARS-CoV-2.
• Developing innovative techniques for studying protein interactions, such as affinity purification-mass spectrometry (AP-MS).

Awards and Honors

Krogan has received several awards and honors for his contributions to science, including:

• The Canada Research Chair in Systems Biology.
• The Sloan Research Fellowship.
• The National Institutes of Health (NIH) Director's New Innovator Award.

Personal Life

Nevan Krogan resides in San Francisco, California, where he continues his research and teaching at UCSF. He is married and has two children.

See Also

• Systems biology
• Protein-protein interaction
• Infectious diseases
• University of California, San Francisco
• Quantitative Biosciences Institute