Noretynodrel

Noretynodrel is a progestin medication which was used in birth control pills and in the treatment of gynecological disorders. It is no longer available for medical use. Noretynodrel is a progestogen, or an agonist of the progesterone receptor, the biological target of progestogens like progesterone. It has weak androgenic and estrogenic activity and no other important hormonal activity.

History

Noretynodrel was introduced for medical use, specifically in birth control pills, in 1957. It was the first progestin to be introduced and was followed by many others thereafter. Noretynodrel was developed by Frank B. Colton at G.D. Searle & Company and was based on the work of Russell Marker and Carl Djerassi.

Medical uses

Noretynodrel was used in birth control pills and in the treatment of gynecological disorders. It was used in combination with an estrogen, usually mestranol, in birth control pills, and was used alone in the treatment of gynecological disorders.

Pharmacology

As a progestin, noretynodrel is a synthetic analogue of progesterone. It has weak androgenic and estrogenic activity and no other important hormonal activity. The medication is a prodrug of ethinylestradiol, an estrogen, in the body.

Society and culture

Noretynodrel, in combination with mestranol, was marketed under a large number of brand names throughout the world. It is no longer available for medical use.

See also

• List of progestogens
• List of androgens/anabolic steroids
• List of estrogens

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