Normethadone

Normethadone is a synthetic opioid analgesic similar to methadone. It is used in the treatment of severe pain and opioid addiction.

Pharmacology

Normethadone is a full agonist at the mu-opioid receptor and has a high affinity for the delta-opioid receptor. It also has NMDA antagonist properties which may help to prevent opioid tolerance.

Medical uses

Normethadone is used in the treatment of severe pain and in the maintenance treatment of opioid addiction. It is also used in the treatment of opioid withdrawal symptoms.

Side effects

The most common side effects of normethadone are similar to those of other opioids and include constipation, nausea, vomiting, dizziness, and sedation.

Contraindications

Normethadone is contraindicated in patients with a known hypersensitivity to normethadone or any of its components. It is also contraindicated in patients with severe respiratory depression, acute or severe bronchial asthma, or hypercarbia.

Interactions

Normethadone can interact with other medications, including other opioids, benzodiazepines, and certain types of antidepressants.

See also

• Methadone
• Opioid
• Opioid receptor
• Opioid withdrawal

References

Normethadone Resources
Need Help Finding a Doctor? Need help finding a doctor or specialist anywhere in the world? Explore our world directory. WikiMD's DocFinder can assist you in locating millions of physicians.	Medical Knowledge Access the latest research - Most recent articles Ongoing trials.

Translate to: East Asian 中文, 日本, 한국어, South Asian हिन्दी, Urdu, বাংলা, తెలుగు, தமிழ், ಕನ್ನಡ,
Southeast Asian Indonesian, Vietnamese, Thai, မြန်မာဘာသာ, European español, Deutsch, français, русский, português do Brasil, Italian, polski