Oxogestone

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Oxogestone is a progestin medication that has been used in hormonal contraception and hormone replacement therapy. It is a synthetic progestogen, which is a type of hormone that mimics the effects of the natural hormone progesterone.

Pharmacology

Oxogestone works by binding to progesterone receptors in the body, which helps regulate the menstrual cycle and maintain pregnancy. It is often used in combination with an estrogen in combined oral contraceptives to prevent ovulation and thus prevent pregnancy.

Medical Uses

Oxogestone has been used in various forms of hormonal contraception, including oral contraceptives, injectable contraceptives, and intrauterine devices. It is also used in hormone replacement therapy for menopausal women to alleviate symptoms such as hot flashes and vaginal atrophy.

Side Effects

Common side effects of oxogestone may include nausea, headache, breast tenderness, and mood changes. Serious side effects can include an increased risk of blood clots, stroke, and heart attack, particularly in women who smoke and are over the age of 35.

History

Oxogestone was first developed in the mid-20th century and has been used in various forms of hormonal contraception since then. It has been studied extensively for its effectiveness and safety in preventing pregnancy and managing menopausal symptoms.

See Also

• Progestin
• Hormonal contraception
• Hormone replacement therapy
• Progesterone
• Combined oral contraceptive pill

External Links

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