Oxymesterone
Oxymesterone is an androgen and anabolic steroid (AAS) medication which was developed in the 1960s and previously used in medicine for a variety of applications. However, it is no longer available for medical use. It is taken by mouth.
Etymology[edit | edit source]
The term "Oxymesterone" is derived from the chemical structure of the compound, which includes an oxygen atom (oxy-) and a methyl group (-mesterone).
Pharmacology[edit | edit source]
Oxymesterone is a synthetic, orally active anabolic-androgenic steroid (AAS). It is a 17α-alkylated AAS, which means it has been altered at the 17th carbon position to survive oral ingestion and the first pass through the liver.
Medical uses[edit | edit source]
Oxymesterone was previously used for medical purposes. It was used in the treatment of anemia and to support weight gain in patients with wasting conditions. However, it is no longer used medically due to concerns about its potential for liver toxicity.
Side effects[edit | edit source]
Potential side effects of Oxymesterone include virilization among women and gynecomastia among men. It can also cause liver damage, cardiovascular complications, and behavioral changes.
Chemistry[edit | edit source]
Oxymesterone is a synthetic estrane steroid and a derivative of testosterone. It is more specifically a derivative of methyltestosterone, which is testosterone with a methyl group added at the C17α position.
History[edit | edit source]
Oxymesterone was first described in the literature in 1960 and was introduced for medical use by 1962. It was developed by the pharmaceutical company Syntex.
Society and culture[edit | edit source]
Oxymesterone has been used in the world of bodybuilding and athletics for its anabolic effects. However, its use is considered illegal and unethical in most competitive sports.
See also[edit | edit source]
Oxymesterone Resources | ||
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Contributors: Prab R. Tumpati, MD