Palmitoleic acid

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Palmitoleic acid


Palmitoleic acid is a monounsaturated fatty acid that is commonly found in both animal and plant fats. It is particularly abundant in marine oils, macadamia nuts, and sea buckthorn oil. Palmitoleic acid is an omega-7 fatty acid, which means that the first double bond in its chemical structure is located seven carbon atoms from the end of the carbon chain.

Chemical Structure[edit | edit source]

Palmitoleic acid has the chemical formula C16H30O2. It is a carboxylic acid with a 16-carbon chain, which is fully saturated except for one double bond. This double bond is in the cis configuration, meaning that the hydrogen atoms adjacent to the double bond are on the same side of the molecule.

Biological Role[edit | edit source]

In the human body, palmitoleic acid is synthesized from palmitic acid by the action of the enzyme stearoyl-CoA desaturase. It is a component of phospholipids, which are a key component of cell membranes. Palmitoleic acid also plays a role in the regulation of fat metabolism. It has been found to increase insulin sensitivity, reduce fat storage in the liver, and improve the body's response to leptin, a hormone that regulates appetite and energy expenditure.

Health Effects[edit | edit source]

Research has suggested that palmitoleic acid may have beneficial effects on health. Some studies have found that higher levels of palmitoleic acid in the blood are associated with a lower risk of type 2 diabetes and heart disease. However, other studies have found no such association, and further research is needed to confirm these findings.

See Also[edit | edit source]

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Contributors: Prab R. Tumpati, MD