Para-bromoamphetamine

Para-bromoamphetamine (PBA), also known as 4-bromoamphetamine (4-BA), is a psychoactive drug and research chemical of the phenethylamine and amphetamine chemical classes. It acts as a serotonin and norepinephrine releasing agent and is therefore classified as a stimulant and entactogen.

Chemistry

Para-bromoamphetamine is a substituted amphetamine featuring a bromine atom attached to the phenyl ring at the 4th position. It is structurally related to amphetamine itself, differing only by the presence of the bromine atom.

Pharmacology

PBA acts primarily as a serotonin and norepinephrine releasing agent. This means it effectively increases the levels of the serotonin and norepinephrine neurotransmitters in the brain by binding to and partially blocking the transporter proteins that normally remove those monoamines from the synaptic cleft. This allows dopamine and norepinephrine to accumulate within the brain, resulting in stimulating and euphoric effects.

Effects

The effects of PBA can vary greatly depending on the dose taken. At lower doses, it can produce mild stimulant effects similar to those of amphetamine. At higher doses, it can produce powerful psychedelic effects, including intense visual hallucinations and a distorted sense of time.

Risks

Like other stimulants and entactogens, PBA carries a risk of neurotoxicity. Chronic use can lead to serious health problems such as cardiovascular disease, neurological damage, and mental health disorders.

Legal Status

PBA is a Schedule I controlled substance in the United States, meaning it is illegal to manufacture, distribute, or possess without a license.

See Also

• Amphetamine
• Methamphetamine
• MDMA
• Phenethylamine