Penmesterol

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Penmesterol


Penmesterol is a synthetic anabolic steroid and a derivative of testosterone. It is classified as an androgen and anabolic steroid (AAS) and has been used in the treatment of various medical conditions.

Chemical Structure and Properties[edit | edit source]

Penmesterol, also known by its chemical name 17α-methyl-4-pregnene-3,20-dione, is a methylated derivative of testosterone. The addition of a methyl group at the 17α position increases its oral bioavailability, making it effective when administered orally.

Medical Uses[edit | edit source]

Penmesterol has been used in the treatment of conditions such as hypogonadism, where the body does not produce enough testosterone. It has also been used to treat certain types of breast cancer in women, due to its anti-estrogenic properties.

Mechanism of Action[edit | edit source]

As an androgen, penmesterol binds to androgen receptors in various tissues, promoting the development and maintenance of male characteristics. It also exhibits anabolic properties, which help in the growth of muscle mass and strength.

Side Effects[edit | edit source]

Like other anabolic steroids, penmesterol can cause a range of side effects. These may include liver toxicity, cardiovascular issues, and endocrine system disruptions. Long-term use can lead to testicular atrophy, gynecomastia, and other hormonal imbalances.

Legal Status[edit | edit source]

The legal status of penmesterol varies by country. In many places, it is classified as a controlled substance due to its potential for abuse and side effects.

See Also[edit | edit source]

References[edit | edit source]

External Links[edit | edit source]

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Contributors: Prab R. Tumpati, MD