Pentedrone

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Pentedrone is a psychoactive drug and research chemical of the cathinone class that has been sold online as a designer drug. It is a derivative of methcathinone and is sometimes referred to as a bath salt.

History[edit | edit source]

Pentedrone was first identified in 2010 within the drug testing industry and has since been sold as a legal high. It is considered a novel psychoactive substance (NPS) due to its recent emergence on the recreational drug market.

Chemistry[edit | edit source]

Pentedrone is a structural analog of methcathinone, with the methylenedioxy group replaced by a phenyl ring. It is a white, crystalline powder with a slight odor. The chemical formula for pentedrone is C12H17NO.

Pharmacology[edit | edit source]

Pentedrone acts as a norepinephrine-dopamine reuptake inhibitor (NDRI), increasing levels of these neurotransmitters in the brain. This results in feelings of euphoria, increased alertness, and increased energy. However, it can also cause negative side effects such as anxiety, paranoia, and insomnia.

Legal Status[edit | edit source]

The legal status of pentedrone varies by country. In the United States, it is a Schedule I drug under the Controlled Substances Act. In the United Kingdom, it is a Class B drug under the Misuse of Drugs Act 1971. Other countries have also banned or restricted the use of pentedrone.

Health Risks[edit | edit source]

The use of pentedrone can lead to a number of health risks. These include cardiovascular problems, neurotoxicity, and psychosis. Long-term use can lead to drug addiction and withdrawal symptoms.

See Also[edit | edit source]

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Contributors: Prab R. Tumpati, MD