Perazine

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Perazine is an antipsychotic drug that belongs to the phenothiazine class. It is primarily used in the treatment of schizophrenia and other psychotic disorders.

Pharmacology[edit | edit source]

Perazine works by blocking dopamine receptors in the brain, which helps to reduce symptoms of psychosis. It also has antihistamine and anticholinergic effects, which can help to reduce symptoms of anxiety and insomnia.

Side Effects[edit | edit source]

Common side effects of perazine include drowsiness, dizziness, and dry mouth. Less common side effects can include tardive dyskinesia, a condition characterized by involuntary movements, and neuroleptic malignant syndrome, a rare but serious condition that can cause fever, muscle stiffness, and altered mental status.

Interactions[edit | edit source]

Perazine can interact with a number of other medications, including other antipsychotics, antidepressants, and antihistamines. It can also interact with alcohol, which can increase the risk of side effects.

Contraindications[edit | edit source]

Perazine is contraindicated in individuals with a known hypersensitivity to phenothiazines, as well as in individuals with certain medical conditions, such as liver disease, heart disease, and certain blood disorders.

See Also[edit | edit source]

Perazine Resources
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Contributors: Prab R. Tumpati, MD