Perifollicular fibroma

Perifollicular fibroma is a rare, benign skin tumor that originates from the hair follicle. It is characterized by the presence of a solitary, small, firm, skin-colored papule. The lesion is usually asymptomatic, but it can sometimes cause discomfort or tenderness. The exact cause of perifollicular fibroma is unknown, but it is believed to be related to genetic factors.

Clinical Presentation

Patients with perifollicular fibroma typically present with a solitary, small, firm, skin-colored papule. The lesion is usually located on the face, neck, or upper trunk. It is usually asymptomatic, but it can sometimes cause discomfort or tenderness. The lesion is usually less than 1 cm in diameter, but larger lesions have been reported.

Diagnosis

The diagnosis of perifollicular fibroma is usually made based on the clinical presentation and histopathological examination. The histopathological features of perifollicular fibroma include a well-circumscribed dermal nodule composed of dense collagen bundles that surround and entraps hair follicles. The overlying epidermis is usually normal.

Treatment

The treatment of perifollicular fibroma usually involves surgical excision. The prognosis is excellent, as the lesion is benign and does not recur after complete excision.

See Also

• Dermatology
• Skin tumor
• Hair follicle
• Benign tumor
• Surgical excision

References

1. Weedon D. Skin Pathology. 2nd ed. London: Churchill Livingstone; 2002.
2. LeBoit PE, Burg G, Weedon D, Sarasain A. World Health Organization Classification of Tumours. Pathology and Genetics of Skin Tumours. Lyon: IARC Press; 2006.

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