Perifollicular fibroma

Perifollicular Fibroma

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Perifollicular fibroma on the skin

Perifollicular fibroma is a benign skin tumor that arises from the connective tissue surrounding a hair follicle. It is considered a type of fibroma, which is a tumor composed mainly of fibrous or connective tissue.

Clinical Presentation

Perifollicular fibromas typically present as small, firm, skin-colored papules. They are most commonly found on the face, neck, and upper trunk. These lesions are usually asymptomatic and are often discovered incidentally during a routine skin examination.

Pathophysiology

The exact cause of perifollicular fibroma is not well understood. It is thought to originate from the perifollicular connective tissue, which is the tissue surrounding the hair follicle. The tumor is composed of fibroblasts and collagen fibers, which are the main components of connective tissue.

Diagnosis

Diagnosis of perifollicular fibroma is primarily clinical, based on the appearance of the lesion. However, a skin biopsy may be performed to confirm the diagnosis. Histologically, perifollicular fibromas show a proliferation of fibroblasts and collagen fibers around a central hair follicle.

Treatment

Treatment is usually not necessary for perifollicular fibromas, as they are benign and asymptomatic. However, if the lesion is cosmetically concerning or if there is uncertainty about the diagnosis, it can be removed surgically. Options for removal include excision, shave biopsy, or laser therapy.

Differential Diagnosis

The differential diagnosis for perifollicular fibroma includes other benign skin lesions such as dermatofibroma, trichofolliculoma, and angiofibroma. It is important to distinguish perifollicular fibroma from these other conditions to ensure appropriate management.

Related Pages

• Fibroma
• Skin tumor
• Hair follicle
• Dermatofibroma