Trichofolliculoma

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Trichofolliculoma is a rare, benign tumor of the hair follicle. It is considered a type of follicular hamartoma, which is a malformation that involves the hair follicle. Trichofolliculomas are typically found on the face, scalp, or neck and are most commonly diagnosed in adults.

Presentation

Trichofolliculomas usually present as small, solitary, skin-colored or slightly erythematous nodules. They are often asymptomatic but can sometimes be associated with a central pore or tuft of hair. The size of the lesion can vary, but it is generally less than 1 cm in diameter.

Histopathology

Histologically, trichofolliculomas are characterized by a central dilated follicle that is surrounded by numerous smaller secondary follicles. The central follicle often contains keratin and hair shafts. The surrounding stroma may show signs of fibrosis and inflammation.

Diagnosis

The diagnosis of trichofolliculoma is primarily based on clinical examination and histopathological findings. A biopsy is usually performed to confirm the diagnosis and to rule out other conditions such as basal cell carcinoma or other adnexal tumors.

Treatment

Treatment is generally not necessary for trichofolliculomas unless they become symptomatic or for cosmetic reasons. If treatment is desired, surgical excision is the most common approach. Other methods such as laser therapy or cryotherapy may also be used.

Prognosis

The prognosis for trichofolliculoma is excellent, as it is a benign lesion with no potential for malignant transformation. Recurrence after surgical excision is rare.

See also

• Hair follicle
• Follicular hamartoma
• Basal cell carcinoma
• Adnexal tumors