Pickwickian syndrome

Pickwickian syndrome, also known as Obesity hypoventilation syndrome (OHS), is a condition characterized by severe obesity and respiratory failure during sleep. The syndrome is named after a character from Charles Dickens' novel, The Pickwick Papers, who exhibited similar symptoms.

Symptoms

The primary symptoms of Pickwickian syndrome include excessive daytime sleepiness, difficulty breathing or shortness of breath, and snoring. Other symptoms may include morning headaches, restless sleep, and night sweats.

Causes

The main cause of Pickwickian syndrome is obesity, which leads to increased pressure on the chest wall and diaphragm, making it difficult for the person to breathe. This can result in hypoxia (low oxygen levels in the blood) and hypercapnia (high carbon dioxide levels in the blood).

Diagnosis

Diagnosis of Pickwickian syndrome typically involves a physical examination, medical history, and various tests such as polysomnography (a sleep study), arterial blood gas analysis, and pulmonary function tests.

Treatment

Treatment for Pickwickian syndrome primarily involves weight loss through diet and exercise. In some cases, Bariatric surgery may be recommended. Other treatments may include Continuous positive airway pressure (CPAP) therapy, BiPAP therapy, or supplemental oxygen.

Prognosis

With proper treatment, the prognosis for individuals with Pickwickian syndrome is generally good. However, if left untreated, the condition can lead to serious complications such as pulmonary hypertension, heart failure, and respiratory failure.

See also

• Sleep apnea
• Obesity
• Respiratory failure

Pickwickian syndrome Resources
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