Pleuropulmonary blastoma
Pleuropulmonary blastoma (PPB) is a rare and malignant type of lung cancer that primarily affects children. It is characterized by the presence of cysts or solid tumors in the lungs or pleura.
Signs and Symptoms[edit | edit source]
The symptoms of pleuropulmonary blastoma can vary greatly depending on the type and stage of the disease. Common symptoms include a persistent cough, difficulty breathing, chest pain, and recurrent lung infections. In some cases, the disease may be asymptomatic and only discovered during a routine medical examination.
Causes[edit | edit source]
The exact cause of pleuropulmonary blastoma is unknown. However, it is believed to be associated with certain genetic mutations. In particular, mutations in the DICER1 gene have been linked to an increased risk of developing this disease.
Diagnosis[edit | edit source]
Diagnosis of pleuropulmonary blastoma typically involves a combination of physical examination, imaging tests such as CT scans or MRI, and biopsy. The definitive diagnosis is made by histopathological examination of the tumor tissue.
Treatment[edit | edit source]
Treatment for pleuropulmonary blastoma usually involves a combination of surgery, chemotherapy, and radiation therapy. The choice of treatment depends on the type and stage of the disease, as well as the patient's overall health.
Prognosis[edit | edit source]
The prognosis for pleuropulmonary blastoma varies widely depending on the type and stage of the disease. Early detection and treatment can significantly improve the prognosis.
See Also[edit | edit source]
References[edit | edit source]
Pleuropulmonary blastoma Resources | |
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Contributors: Prab R. Tumpati, MD