Postorgasmic illness syndrome

Postorgasmic illness syndrome (POIS) is a rare and poorly understood medical condition characterized by a cluster of debilitating symptoms that occur shortly after orgasm and can last for several days. The condition primarily affects men, although there have been a few reported cases in women.

Symptoms

The symptoms of POIS can vary widely among individuals but commonly include:

• Severe fatigue
• Muscle pain
• Flu-like symptoms
• Cognitive dysfunction (often referred to as "brain fog")
• Irritability
• Depression
• Anxiety
• Headache
• Fever
• Sore throat

Causes

The exact cause of POIS is not well understood. Several hypotheses have been proposed, including:

• Autoimmune response: Some researchers believe that POIS may be an autoimmune response to semen.
• Hormonal imbalance: Fluctuations in hormone levels post-orgasm may contribute to the symptoms.
• Neurological factors: Abnormalities in the nervous system may play a role.

Diagnosis

Diagnosing POIS can be challenging due to its rarity and the lack of specific diagnostic criteria. A thorough medical history and physical examination are essential. Allergy testing and hormonal assays may also be conducted to rule out other conditions.

Treatment

There is no standardized treatment for POIS, and management often involves a combination of approaches:

• Medications: Antihistamines, anti-inflammatory drugs, and antidepressants may provide symptom relief.
• Behavioral therapy: Cognitive-behavioral therapy (CBT) can help manage the psychological impact of the condition.
• Lifestyle modifications: Regular exercise, a balanced diet, and adequate sleep may help alleviate symptoms.

Prognosis

The prognosis for individuals with POIS varies. Some people may experience a reduction in symptoms over time, while others may continue to suffer from severe symptoms. Ongoing research aims to better understand the condition and develop more effective treatments.

Related Pages

• Autoimmune disease
• Hormonal imbalance
• Cognitive dysfunction
• Chronic fatigue syndrome
• Depression
• Anxiety

Resources

Latest articles - Postorgasmic illness syndrome

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Source: Data courtesy of the U.S. National Library of Medicine. Since the data might have changed, please query MeSH on Postorgasmic illness syndrome for any updates.

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