Probarbital

Probarbital is a barbiturate derivative that was first synthesized in 1924. It is a long-acting barbiturate that was used for the treatment of insomnia and other sleep disorders. Probarbital was withdrawn from the market in the 1980s due to the risk of abuse and addiction.

History

Probarbital was first synthesized in 1924 by the German pharmaceutical company Bayer. It was marketed under the brand name Luminal and was widely used for the treatment of insomnia and other sleep disorders. However, due to the risk of abuse and addiction, Probarbital was withdrawn from the market in the 1980s.

Pharmacology

Probarbital is a long-acting barbiturate. It works by increasing the activity of the GABA neurotransmitter, which helps to slow down brain activity. This results in a calming effect, which can help to induce sleep.

Side Effects

The side effects of Probarbital can include drowsiness, dizziness, and confusion. In severe cases, it can cause respiratory depression and death. Long-term use of Probarbital can lead to physical dependence and withdrawal symptoms.

See Also

• Barbiturate
• Insomnia
• GABA

References

Probarbital Resources
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