Proligestone

Proligestone is a synthetic, steroidal progestin that is used in veterinary medicine to control estrus in animals. It is not used in humans. Proligestone is marketed under the brand name Delvosteron.

Pharmacology

Proligestone is a progestin, or a synthetic progestogen, and hence is an agonist of the progesterone receptor, the biological target of progestogens like progesterone. It has strong progestogenic effects and no other important hormonal activity.

Chemistry

Proligestone, also known as 17α-acetoxy-6-chloropregna-4,6-diene-3,20-dione, is a synthetic pregnane steroid and a derivative of progesterone. It is more specifically a derivative of 17α-hydroxyprogesterone and is a member of the gonane (18-gonane) group of progestins.

History

Proligestone was introduced for veterinary use in the 1970s.

Society and culture

Proligestone is marketed for veterinary use under the brand name Delvosteron.

See also

• List of progestogens
• List of progestogen esters
• List of veterinary drugs

Proligestone Resources
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