Propiram

From WikiMD's Food, Medicine & Wellness Encyclopedia

Propiram is a powerful opioid analgesic drug that is used for the treatment of severe pain. It is a derivative of pethidine (meperidine) and is chemically related to other drugs such as alfentanil and remifentanil.

Pharmacology[edit | edit source]

Propiram acts as a mu-opioid receptor agonist. It has a high affinity for the mu-opioid receptor, which is responsible for its analgesic effects. The drug also has a moderate affinity for the delta-opioid receptor and a low affinity for the kappa-opioid receptor.

Medical uses[edit | edit source]

Propiram is used for the treatment of severe pain. It is often used in combination with other analgesics such as paracetamol (acetaminophen) or nonsteroidal anti-inflammatory drugs (NSAIDs) to enhance its analgesic effects.

Side effects[edit | edit source]

Like other opioids, propiram can cause a range of side effects. These can include nausea, vomiting, constipation, drowsiness, and respiratory depression. In severe cases, it can cause opioid overdose, which can be fatal.

Legal status[edit | edit source]

Propiram is a Schedule II controlled substance in the United States, meaning it has a high potential for abuse and dependence. It is also a controlled substance in many other countries.

See also[edit | edit source]

Propiram Resources
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Contributors: Prab R. Tumpati, MD