Propoxyphene hydrochloride

Propoxyphene Hydrochloride is a narcotic analgesic that was formerly used in the treatment of mild to moderate pain. It is a member of the opioid class of drugs, which also includes substances like morphine, codeine, and oxycodone.

Pharmacology

Propoxyphene Hydrochloride works by binding to opioid receptors in the brain and spinal cord, which are involved in the transmission and perception of pain. This binding action inhibits the reuptake of norepinephrine and serotonin, which can help to alleviate pain.

Medical Uses

Propoxyphene Hydrochloride was primarily used to treat mild to moderate pain. It was also sometimes used as a cough suppressant, due to its effects on the central nervous system. However, its use has been largely discontinued due to concerns about its safety and effectiveness.

Side Effects

Common side effects of Propoxyphene Hydrochloride include dizziness, sedation, nausea, and vomiting. More serious side effects can include respiratory depression, addiction, and overdose.

History

Propoxyphene Hydrochloride was first synthesized in the 1950s and was widely used for several decades. However, it was withdrawn from the market in many countries in the early 21st century due to concerns about its safety and effectiveness.

See Also

• Opioid
• Narcotic analgesic
• Opioid receptors
• Norepinephrine
• Serotonin