Quinagolide
Quinagolide is a non-ergoline dopamine agonist which is used in the treatment of hyperprolactinemia. It is a selective D2 receptor agonist, which has been shown to suppress the secretion of prolactin in humans.
Mechanism of action[edit | edit source]
Quinagolide works by stimulating dopamine D2 receptors in the pituitary gland. This reduces the production of prolactin, a hormone that stimulates the production of breast milk. By reducing the levels of prolactin in the body, quinagolide can help to treat conditions caused by high levels of this hormone, such as amenorrhea (absence of menstruation), galactorrhea (abnormal milk production), and infertility.
Uses[edit | edit source]
Quinagolide is used to treat hyperprolactinemia, a condition characterized by high levels of prolactin in the blood. This can cause various symptoms, including irregular menstrual periods, infertility, and unwanted breast milk production. Quinagolide can help to normalize prolactin levels and alleviate these symptoms.
Side effects[edit | edit source]
Like all medicines, quinagolide can cause side effects, although not everybody gets them. The most common side effects include nausea, headache, dizziness, and fatigue. If these side effects persist or become bothersome, it is important to contact a healthcare provider.
Contraindications[edit | edit source]
Quinagolide should not be used in people who are allergic to any of the ingredients in the medication. It should also not be used in people with certain medical conditions, such as uncontrolled hypertension or psychosis. It is important to discuss any medical conditions with a healthcare provider before starting treatment with quinagolide.
Interactions[edit | edit source]
Quinagolide can interact with other medications, which can affect how it works or increase the risk of side effects. It is important to tell a healthcare provider about all the medications being taken, including prescription and over-the-counter medicines, vitamins, and herbal supplements.
See also[edit | edit source]
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Contributors: Prab R. Tumpati, MD
