Reinke's edema

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Reinke's edema
Reinke's edema
Synonyms Polypoid corditis, smoker's polyps
Pronounce N/A
Specialty N/A
Symptoms Hoarseness, voice changes, dyspnea
Complications Airway obstruction
Onset Gradual
Duration Long-term
Types N/A
Causes Smoking, vocal abuse, gastroesophageal reflux disease
Risks Smoking, chronic vocal strain, reflux
Diagnosis Laryngoscopy, stroboscopy
Differential diagnosis Vocal cord nodules, vocal cord polyps, laryngitis
Prevention N/A
Treatment Smoking cessation, voice therapy, surgery
Medication N/A
Prognosis Good with treatment
Frequency Common in smokers
Deaths N/A


Vocal fold animation
Laryngoscope

Reinke's edema is a medical condition characterized by the swelling of the vocal cords due to fluid accumulation in the Reinke's space, a potential space located between the vocal ligament and the overlying vocal fold mucosa. This condition is also known as polypoid degeneration, edematous hyptertrophy or smoker's voice due to its common occurrence in heavy smokers.

Causes[edit | edit source]

The primary cause of Reinke's edema is chronic irritation of the vocal cords. This can be due to smoking, GERD, overuse of the voice, and endocrine disorders.

Symptoms[edit | edit source]

The main symptom of Reinke's edema is a low, rough, hoarse voice. Other symptoms can include dysphonia, dyspnea, and stridor.

Diagnosis[edit | edit source]

Reinke's edema is diagnosed through a combination of patient history, physical examination, and laryngoscopy. Other diagnostic tools can include stroboscopy, acoustic analysis, and videokymography.

Treatment[edit | edit source]

Treatment for Reinke's edema can include lifestyle changes, medication, and surgery. Lifestyle changes can include quitting smoking and managing GERD. Medications can include corticosteroids and antibiotics. Surgery, known as microflap surgery, is used in severe cases.

Prognosis[edit | edit source]

The prognosis for Reinke's edema is generally good with treatment. However, if left untreated, it can lead to permanent voice changes and breathing difficulties.

See also[edit | edit source]

References[edit | edit source]

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Contributors: Prab R. Tumpati, MD