Renalase

Renalase (also known as RNLS) is a protein that in humans is encoded by the RNLS gene. Renalase is secreted by the kidneys and metabolizes circulating catecholamines. It is a flavoprotein that is secreted into the blood by the kidneys and is then rapidly taken up by the heart and blood vessels.

Function

Renalase is a monoamine oxidase that specifically metabolizes circulating catecholamines (such as adrenaline and noradrenaline). It is thought to play a crucial role in the regulation of heart rate and blood pressure, and may be involved in kidney function and cardiovascular disease.

Clinical significance

Renalase is being studied for its potential role in treating heart disease, high blood pressure, and kidney disease. It may also have potential as a therapeutic target for cancer treatment.

See also

• Kidney disease
• Heart disease
• Blood pressure
• Catecholamines
• Monoamine oxidase

References

Renalase Resources
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