Robert Tigerstedt

Robert Tigerstedt

Robert Tigerstedt (17 March 1853 – 22 July 1923) was a Finnish physiologist known for his groundbreaking work in the field of cardiovascular physiology. His most notable contribution to medicine and physiology was the discovery of the renin-angiotensin system, a hormone system that regulates blood pressure and fluid balance. Born in Helsinki, Finland, Tigerstedt began his medical studies at the University of Helsinki, where he later became a professor of physiology. Throughout his career, he was deeply involved in research that spanned various aspects of physiology, but his work on the kidneys and cardiovascular system had the most lasting impact on the field. In 1898, together with his student Per Bergman, Tigerstedt conducted a series of experiments that led to the discovery of renin, an enzyme secreted by the kidneys that plays a crucial role in the body's regulation of blood pressure. This discovery was seminal in the development of the renin-angiotensin system concept, which has since become fundamental in understanding hypertension and has led to the development of several antihypertensive drugs. Tigerstedt's contributions to physiology were not limited to his research on the renin-angiotensin system. He was also an influential educator and author, writing one of the most comprehensive physiology textbooks of his time, "Textbook of Human Physiology." His work in developing experimental methods in physiology laid the groundwork for future research in the field. Despite his significant contributions, Tigerstedt's work was not widely recognized until after his death. Today, he is celebrated as a pioneer in cardiovascular physiology and his discoveries continue to influence the field of medicine. Throughout his life, Tigerstedt received several honors and was a member of various scientific societies, reflecting his status as a respected figure in the scientific community. His legacy is preserved through the Robert Tigerstedt Society, which promotes research and education in physiology in Finland.

See also

• Renin-angiotensin system
• Physiology
• Cardiovascular system
• Hypertension