SNB-19
SNB-19 | |
---|---|
Synonyms | N/A |
Pronounce | N/A |
Specialty | N/A |
Symptoms | Brain tumor symptoms |
Complications | Seizures, neurological deficits |
Onset | Varies |
Duration | Chronic |
Types | N/A |
Causes | Genetic mutations |
Risks | Radiation exposure, family history |
Diagnosis | MRI, CT scan, biopsy |
Differential diagnosis | N/A |
Prevention | N/A |
Treatment | Surgery, radiation therapy, chemotherapy |
Medication | N/A |
Prognosis | Variable |
Frequency | Rare |
Deaths | N/A |
SNB-19 is a human glioblastoma cell line used extensively in cancer research. Glioblastoma is a type of brain tumor that is highly aggressive and difficult to treat. The SNB-19 cell line is derived from a glioblastoma multiforme tumor and is used to study the molecular biology of glioblastoma, as well as to test potential therapeutic agents.
Characteristics[edit | edit source]
SNB-19 cells exhibit many of the typical features of glioblastoma cells, including rapid proliferation, invasiveness, and the ability to form tumors in animal models. These cells are anchorage-independent, meaning they can grow without being attached to a surface, a characteristic of malignant cells.
Research Applications[edit | edit source]
The SNB-19 cell line is used in various research applications, including:
- Drug screening: Testing the efficacy of new anticancer drugs.
- Genetic studies: Understanding the role of specific genes in tumor development and progression.
- Signal transduction: Investigating the signaling pathways involved in cell growth and apoptosis.
Culturing SNB-19 Cells[edit | edit source]
SNB-19 cells are typically cultured in Dulbecco's Modified Eagle Medium (DMEM) supplemented with fetal bovine serum (FBS) and antibiotics. They require a humidified atmosphere with 5% carbon dioxide at 37°C for optimal growth.
See Also[edit | edit source]
References[edit | edit source]
External Links[edit | edit source]
- [Link to relevant research articles]
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Contributors: Prab R. Tumpati, MD