SNB-19
SNB-19 is a glioblastoma cell line that is commonly used in medical research to study the biology of brain tumors. This cell line was originally derived from a patient with glioblastoma, the most aggressive type of primary brain tumor.
History[edit | edit source]
The SNB-19 cell line was established in the late 1970s by the Neurological Surgery department at the University of California, San Francisco. The cell line was derived from a tumor sample taken from a patient undergoing surgery for glioblastoma. Since its establishment, SNB-19 has been widely used in research laboratories around the world to study the biology of glioblastoma and to test potential therapeutic strategies.
Characteristics[edit | edit source]
SNB-19 cells are characterized by their rapid growth and high level of invasiveness, which closely mimic the behavior of glioblastoma tumors in patients. These cells also express high levels of epidermal growth factor receptor (EGFR), a protein that is often overexpressed in glioblastoma and is associated with poor prognosis.
Use in Research[edit | edit source]
SNB-19 cells are used in a variety of research applications, including studies of cell proliferation, cell migration, and cell invasion. They are also used in drug screening experiments to identify potential new treatments for glioblastoma.
See Also[edit | edit source]
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Contributors: Prab R. Tumpati, MD
