Smouldering myeloma

From WikiMD's Wellness Encyclopedia

Smouldering myeloma (also known as SMM) is a slow-growing type of myeloma that does not cause any symptoms. It is considered a pre-cancerous condition and is often discovered during routine blood tests.

Overview[edit | edit source]

Smouldering myeloma is characterized by the presence of abnormal plasma cells in the bone marrow and a high level of monoclonal protein (M protein) in the blood. However, unlike active myeloma, it does not cause any damage to the body and does not require immediate treatment.

Diagnosis[edit | edit source]

The diagnosis of smouldering myeloma is based on the following criteria:

  • Presence of 10% or more abnormal plasma cells in the bone marrow
  • High level of M protein in the blood
  • Absence of anemia, high calcium levels, kidney damage, or bone lesions

Treatment[edit | edit source]

Currently, there is no standard treatment for smouldering myeloma. Instead, patients are closely monitored for signs of progression to active myeloma. This approach is known as "watchful waiting" or "active surveillance".

Prognosis[edit | edit source]

The prognosis for smouldering myeloma varies greatly. Some patients may never develop active myeloma, while others may progress to active myeloma within a few years.

See also[edit | edit source]

References[edit | edit source]


Smouldering myeloma Resources
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Contributors: Prab R. Tumpati, MD