Sodium cholate

Sodium cholate is a sodium salt of cholic acid, a primary bile acid produced by the liver. It is a white crystalline substance that is soluble in water and alcohol. Sodium cholate is used in the medical and research fields due to its properties as a biological detergent.

Chemical Properties

Sodium cholate has the chemical formula C24H39NaO5. It is a hydrophilic compound, meaning it is attracted to water molecules. This property makes it useful in the solubilization of lipids and proteins in research settings.

Biological Role

In the body, sodium cholate is a component of bile, a fluid produced by the liver to aid in the digestion of dietary fats. It acts as an emulsifier, breaking down large fat globules into smaller ones that can be more easily digested and absorbed by the body.

Medical and Research Use

Sodium cholate is used in the medical field as a choleretic, a substance that stimulates the liver to produce more bile. It is also used in research as a biological detergent to solubilize and isolate proteins and lipids.

Safety

While sodium cholate is a naturally occurring substance in the body, excessive amounts can be harmful. It can cause irritation to the eyes, skin, and respiratory tract if not handled properly. Ingestion can lead to nausea, vomiting, and diarrhea.

See Also

• Cholic acid
• Bile acid
• Sodium salt
• Liver