Spiroxatrine

Spiroxatrine is a drug which acts as a selective antagonist at both the 5-HT1A and α2-adrenergic receptor. It is an analog of spiperone and also has some dopamine antagonist effects.

Pharmacology

Spiroxatrine is a potent and selective antagonist for the 5-HT1A and α2-adrenergic receptor. It has a high affinity for these receptors and acts by blocking their actions. This makes it useful in the study of these receptors and it has been used in scientific research for this purpose.

Chemistry

Spiroxatrine is an analog of spiperone, a potent dopamine antagonist. It differs from spiperone in the substitution of one of the aromatic rings with a tetrahydrofuran ring. This change gives spiroxatrine its unique pharmacological properties.

Uses

Spiroxatrine has been used in scientific research to study the 5-HT1A and α2-adrenergic receptor. It has been used in studies investigating the role of these receptors in depression, anxiety, and other psychiatric disorders.

See also

• 5-HT1A receptor
• Alpha-2 adrenergic receptor
• Spiperone

Spiroxatrine Resources
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