TAS2R5

TAS2R5 or Taste receptor type 2 member 5 is a protein that in humans is encoded by the TAS2R5 gene. It is a part of the bitter taste receptor family, which is a group of G protein-coupled receptors.

Function

TAS2R5 is a member of the TAS2R (Taste receptor, type 2) gene family. The TAS2Rs are expressed in the taste receptor cells of the tongue and palate epithelia. They respond to bitter compounds, which are naturally occurring in many foods and can be toxic. This receptor is involved in the perception of bitterness and enables the body to react in response to harmful substances.

Gene

The TAS2R5 gene is located on chromosome 7, specifically at 7q31.3. It spans approximately 1.6 kilobases and consists of a single coding exon. The gene is expressed in the gustatory cells located in taste buds.

Clinical significance

Variations in the TAS2R5 gene have been associated with differences in taste perception of certain bitter compounds. A better understanding of taste perception may lead to methods for improving diet and health, as well as for treating taste and smell disorders.

See also

• TAS2R38
• TAS2R16
• Taste receptor

External links

• GeneCard for TAS2R5