TH-PVP

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TH-PVP


TH-PVP is a synthetic stimulant of the cathinone class that produces effects similar to amphetamine. It is chemically related to pyrovalerone compounds such as MDPV and is one of the key ingredients in many synthetic cannabis products. TH-PVP is often sold as a designer drug and is known for its potent psychostimulant effects.

Chemistry[edit | edit source]

TH-PVP, or α-pyrrolidinopentiophenone, is a compound of the substituted cathinone and substituted pyrrolidine chemical classes. Its structure is comprised of a phenyl ring bound to an amino (NH2) group through an ethyl chain with an additional alkyl substituent at Rα.

Pharmacology[edit | edit source]

TH-PVP acts as a potent norepinephrine-dopamine reuptake inhibitor (NDRI), but its effects on serotonin are not well understood. It is thought to enhance the release of these neurotransmitters, leading to increased levels in the synaptic cleft and producing stimulant effects.

Effects[edit | edit source]

The effects of TH-PVP can vary greatly depending on the dose and the user's individual physiology. Common effects include stimulation, euphoria, increased alertness and focus, and increased sociability. However, higher doses can lead to negative effects such as anxiety, paranoia, and psychosis.

Legal Status[edit | edit source]

The legal status of TH-PVP varies by country. In many countries, it is classified as a controlled substance due to its potential for abuse and addiction.

See Also[edit | edit source]



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Contributors: Prab R. Tumpati, MD