Talbutal

Talbutal is a barbiturate that was once commonly used as a sleeping pill (or hypnotic). However, it has been largely replaced by newer drugs with fewer side effects. It is still used in some cases for the treatment of insomnia and other sleep disorders, particularly when other treatments have failed. It is also used in veterinary medicine for the euthanasia of small animals.

History

Talbutal was first synthesized in the early 20th century. It was widely used as a sleeping aid until the 1970s, when it began to be replaced by newer drugs such as benzodiazepines. Despite its decreased use in humans, it remains in use in veterinary medicine.

Pharmacology

Like other barbiturates, talbutal works by increasing the activity of the gamma-aminobutyric acid (GABA) neurotransmitter, which inhibits the activity of the central nervous system. This results in sedation, hypnosis, and decreased anxiety. However, it can also lead to dependence and withdrawal symptoms if used for extended periods.

Side effects

Common side effects of talbutal include drowsiness, dizziness, and loss of coordination. More serious side effects can include respiratory depression, addiction, and, in high doses, coma or death.

Legal status

In many countries, including the United States, talbutal is a controlled substance due to its potential for abuse and addiction.

See also

• Barbiturate
• Insomnia
• Benzodiazepine

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