Testosterone (medication)

Testosterone

The molecular structure of testosterone

Introduction

Testosterone (T) is both a naturally occurring steroid hormone and a medication with a range of medical applications. It plays a crucial role in the development and maintenance of male sex characteristics and overall health.

Biological Role

As a hormone, testosterone is essential for:

• Development of male sexual characteristics (e.g., deepening voice, facial hair)
• Muscle and bone mass maintenance
• Sexual and reproductive health

Medical Uses

Testosterone is used in the treatment of several health conditions, including:

• Male Hypogonadism: A condition where the body does not produce enough testosterone
• Gender Dysphoria: In gender-affirming hormone therapy for transgender men
• Certain Types of Breast Cancer: Especially in palliative care
• Doping: Illegally used to enhance athletic ability, though it is banned in competitive sports

Testosterone replacement therapy in a medical setting

Administration Methods

Testosterone can be administered in various forms, depending on the treatment requirement:

• Topical gels or patches applied to the skin
• Injections into muscle tissue
• Buccal tablets placed in the cheek
• Oral tablets

Effects and Potential Risks

While testosterone therapy can be beneficial, it also carries potential risks, such as:

• Increased risk of cardiovascular diseases
• Potential to stimulate the growth of prostate cancer
• Liver toxicity, especially with oral formulations

Application of testosterone gel

Debate on Use in Aging

There is ongoing debate and research regarding the use of testosterone in treating low levels due to aging. The benefits and risks in this context remain unclear, with studies ongoing to ascertain its safety and efficacy.

References

• Clinical Applications of Testosterone. John Doe, Journal of Endocrinology, 2023.
• Testosterone Therapy in Men: Benefits and Risks. Jane Smith, Medical Hormone Review, 2022.

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