Testosterone phenylacetate
Testosterone Phenylacetate is an androgen and anabolic steroid (AAS) medication, which is used primarily in the treatment of low testosterone levels in men. It is also used in hormone therapy for transgender men. It is given by injection into muscle usually once every one to two weeks.
Pharmacology[edit | edit source]
Testosterone phenylacetate is a synthetic ester that is attached to the testosterone molecule. This modification allows the testosterone to be released slowly over a period of time after injection. The phenylacetate ester is a medium-length ester that falls between the shorter propionate ester and the longer cypionate and enanthate esters in terms of release rate and duration of action.
Medical Uses[edit | edit source]
Testosterone phenylacetate is used in androgen replacement therapy. It is specifically used to treat male hypogonadism and symptoms of low testosterone levels. These symptoms can include reduced libido, erectile dysfunction, depression, fatigue, decreased muscle mass and bone density, and anemia.
In addition, testosterone phenylacetate is used in hormone therapy for transgender men. This involves the use of testosterone to develop male secondary sexual characteristics, such as increased muscle and bone mass, deepening of the voice, growth of body and facial hair, and changes in fat distribution.
Side Effects[edit | edit source]
Like all androgens, testosterone phenylacetate can have side effects. These can include acne, increased body and facial hair growth, masculinization, voice deepening, and changes in sexual desire. More serious side effects can include cardiovascular complications, such as increased risk of heart attack and stroke, and liver problems.
See Also[edit | edit source]
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Contributors: Prab R. Tumpati, MD