Tetradecylthioacetic acid

Tetradecylthioacetic acid

Tetradecylthioacetic Acid (TTA) is a synthetic fatty acid known for its involvement in various biological processes, including lipid metabolism, inflammation, and cell proliferation. It is often used in research settings to study these processes.

Chemical Structure

TTA is a 16-carbon sulfur-containing fatty acid. Its structure is similar to that of palmitic acid, a common saturated fatty acid, but with a sulfur atom replacing one of the methylene groups in the chain.

Biological Effects

TTA has been shown to have several effects on the body's metabolism. It can increase mitochondrial fatty acid oxidation, reduce lipogenesis, and increase thermogenesis, leading to reduced body weight and improved insulin sensitivity in animal models. It also has anti-inflammatory effects and can inhibit cell proliferation, making it of interest for potential use in treating diseases such as cancer and atherosclerosis.

Research Use

Due to its effects on metabolism and cell proliferation, TTA is often used in research settings. It can be used to study the mechanisms of fatty acid oxidation and thermogenesis, as well as the effects of fatty acids on inflammation and cell proliferation. It has also been used in studies investigating potential treatments for obesity, diabetes, and cardiovascular disease.

Safety and Toxicity

While TTA has been shown to have beneficial effects on metabolism and inflammation, its safety and toxicity have not been fully established. Some studies have suggested that it may have potential side effects, including liver enlargement and changes in lipid levels. More research is needed to fully understand the safety and potential risks of TTA.

See Also

• Fatty acid
• Lipid metabolism
• Cell proliferation
• Inflammation