Tetrahydrothiophene

From WikiMD's Food, Medicine & Wellness Encyclopedia

Tetrahydrothiophene is a organic compound with the formula (C4H8S). Also known as thiolane, it is a cyclic thioether that is a structural analog of cyclopentane and thiophene. It is a colorless liquid with an intensely foul odor, reminiscent of garlic or rotten eggs. Tetrahydrothiophene is used as a flavoring agent and an odorant in natural gas, mainly due to its potent and recognizable smell.

Structure and Synthesis[edit | edit source]

Tetrahydrothiophene is a five-membered ring with four carbon atoms and one sulfur atom. The synthesis of tetrahydrothiophene involves the reaction of 1,4-dibromobutane with sodium sulfide in a process known as a nucleophilic substitution reaction.

Uses[edit | edit source]

Tetrahydrothiophene is used as a flavoring agent in food industry. It is also used as an odorant for natural gas, which is otherwise odorless. This allows leaks to be detected by smell. In the laboratory, it can be used as a solvent and a building block to other chemical compounds.

Safety[edit | edit source]

Tetrahydrothiophene is a flammable liquid and its vapors can form explosive mixtures with air. It is harmful if swallowed, inhaled, or comes into contact with the skin. It can cause eye and skin irritation, respiratory irritation, and may be harmful to the aquatic environment.

See also[edit | edit source]


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Contributors: Prab R. Tumpati, MD