Theacrine

Theacrine is a purine alkaloid found in Cupuaçu (Theobroma grandiflorum) and in a Chinese tea known as kucha (Camellia assamica var. kucha). It shows anti-inflammatory and analgesic effects and appears to affect adenosine signaling in a manner similar to caffeine.

Chemistry

Theacrine is a small alkaloid molecule. It is structurally similar to caffeine, with the addition of a ketone group and an additional methyl group. Theacrine is soluble in water and has a bitter taste.

Pharmacology

Theacrine acts as an adenosine receptor antagonist and a dopamine receptor agonist. It has been shown to have anti-inflammatory and analgesic effects, and to increase locomotor activity. Theacrine also appears to affect adenosine signaling in a manner similar to caffeine, but with less potency.

Uses

Theacrine is used as a stimulant in dietary supplements, often in combination with caffeine. It is also used in traditional Chinese medicine.

Safety

The safety of theacrine is not well studied. However, it is generally considered safe when used in moderation.

See also

• Caffeine
• Adenosine receptor
• Dopamine receptor
• Alkaloid
• Cupuaçu
• Kucha

Theacrine Resources
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