Thiopropazate

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Thiopropazate is a typical antipsychotic of the phenothiazine class. It was introduced in the 1960s by Rhône-Poulenc and is used in Europe, including Austria, Belgium, Czech Republic, France, and Slovakia. Thiopropazate has similar effects to other typical antipsychotics, and is used for the treatment of schizophrenia and other types of psychosis.

Pharmacology[edit | edit source]

Thiopropazate is a D2 receptor antagonist. It works by blocking the action of dopamine, a neurotransmitter in the brain that is involved in mood and behavior. This can help to reduce symptoms of psychosis, such as hallucinations, delusions, and disorganized thinking.

Side effects[edit | edit source]

Like other typical antipsychotics, thiopropazate can cause a range of side effects. These can include drowsiness, dizziness, dry mouth, constipation, and blurred vision. More serious side effects can include tardive dyskinesia, a condition characterized by involuntary movements, and neuroleptic malignant syndrome, a rare but potentially life-threatening reaction to antipsychotic drugs.

See also[edit | edit source]

Thiopropazate Resources
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Contributors: Prab R. Tumpati, MD