Trestolone acetate

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Trestolone acetate (also known as 7α-methyl-19-nortestosterone (MENT), MENT Acetate or MENT Act) is a synthetic and injected anabolic–androgenic steroid (AAS) and a derivative of nandrolone (19-nortestosterone) which was never marketed. It is a potent agonist of the androgen receptor (AR) and hence is a powerful androgen and anabolic.

Chemistry[edit | edit source]

Trestolone acetate, as mentioned, is a synthetic derivative of nandrolone. It is characterized by a modification at the 7th position with a methyl group which increases its androgenic potency. The acetate ester in trestolone acetate increases its solubility in oil, which allows the drug to have a longer half-life and to be provided in an injectable form.

Pharmacology[edit | edit source]

As an AAS, trestolone acetate is an agonist of the androgen receptor, the biological target of androgens like testosterone and dihydrotestosterone. It has strong androgenic effects and moderate anabolic effects, which make it useful for producing masculinization and suitable for androgen replacement therapy. Trestolone acetate is a potent agonist of the androgen receptor and hence is a powerful androgen.

Medical uses[edit | edit source]

Trestolone acetate is currently being researched for its potential uses in male contraception and testosterone replacement therapy. Due to its potent androgenic effects, it can effectively suppress the production of gonadotropins and prevent the testes from producing sperm, making it a potential candidate for male contraception. In testosterone replacement therapy, it can be used to restore normal levels of testosterone in those with low testosterone levels.

Side effects[edit | edit source]

Like other AAS, trestolone acetate has potential side effects, most notably its virilizing effects such as acne, increased body and facial hair growth, and deepening of the voice. It can also have adverse effects on cholesterol levels, liver function, and cardiovascular health.

See also[edit | edit source]

References[edit | edit source]

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