Triple X syndrome
Triple X syndrome, also known as Trisomy X or 47,XXX, is a genetic condition found in females, characterized by the presence of an extra X chromosome in each of a person's cells.[1]
.png)
Genetic Basis[edit | edit source]
.svg)
Typically, females have two X chromosomes. However, in Triple X syndrome, they have three. This condition results from a random event during the formation of reproductive cells (ovum and sperm). An error in cell division called nondisjunction can result in reproductive cells with an abnormal number of chromosomes.[2]
Clinical Manifestations[edit | edit source]
Most females with triple X syndrome have normal development and experience usual childhood, adolescence, and adult life. Some may have slightly taller stature and may face learning difficulties, particularly in language and speech skills. There may also be mild developmental delays and behavioral and emotional difficulties. Physical features can vary and often are not noticeable. Some girls and women experience menstrual irregularities and have a higher risk of premature ovarian failure.[3]
Diagnosis[edit | edit source]
Triple X syndrome can be diagnosed prenatally through amniocentesis or chorionic villus sampling (CVS). Postnatally, it can be identified through a karyotype analysis, where a blood sample is used to count and evaluate chromosomes.[4]
Management and Prognosis[edit | edit source]
Management of triple X syndrome involves addressing any physical, developmental, or emotional issues as they arise. Speech and language therapy, as well as educational support, can be beneficial. The prognosis for girls and women with triple X syndrome is typically good, as they can lead healthy, normal lives.[5]
See Also[edit | edit source]
References[edit | edit source]
- ↑ "Triple X Syndrome". Genetics Home Reference. Retrieved 2023-05-18.
- ↑ "Triple X Syndrome". Genetics Home Reference. Retrieved 2023-05-18.
- ↑ "Triple X Syndrome". National Organization for Rare Disorders. Retrieved 2023-05-18.
- ↑ "Triple X Syndrome". Mayo Clinic. Retrieved 2023-05-18.
- ↑ "Triple X Syndrome". National Institute of Child Health and Human Development. Retrieved 2023-05-18.
| Triple X syndrome Resources | |
|---|---|
|
 |
Search WikiMD
Ad.Tired of being Overweight? Try W8MD's physician weight loss program.
Semaglutide (Ozempic / Wegovy and Tirzepatide (Mounjaro / Zepbound) available.
Advertise on WikiMD
|
WikiMD's Wellness Encyclopedia |
| Let Food Be Thy Medicine Medicine Thy Food - Hippocrates |
Translate this page: - East Asian
中文,
日本,
한국어,
South Asian
हिन्दी,
தமிழ்,
తెలుగు,
Urdu,
ಕನ್ನಡ,
Southeast Asian
Indonesian,
Vietnamese,
Thai,
မြန်မာဘာသာ,
বাংলা
European
español,
Deutsch,
français,
Greek,
português do Brasil,
polski,
română,
русский,
Nederlands,
norsk,
svenska,
suomi,
Italian
Middle Eastern & African
عربى,
Turkish,
Persian,
Hebrew,
Afrikaans,
isiZulu,
Kiswahili,
Other
Bulgarian,
Hungarian,
Czech,
Swedish,
മലയാളം,
मराठी,
ਪੰਜਾਬੀ,
ગુજરાતી,
Portuguese,
Ukrainian
Medical Disclaimer: WikiMD is not a substitute for professional medical advice. The information on WikiMD is provided as an information resource only, may be incorrect, outdated or misleading, and is not to be used or relied on for any diagnostic or treatment purposes. Please consult your health care provider before making any healthcare decisions or for guidance about a specific medical condition. WikiMD expressly disclaims responsibility, and shall have no liability, for any damages, loss, injury, or liability whatsoever suffered as a result of your reliance on the information contained in this site. By visiting this site you agree to the foregoing terms and conditions, which may from time to time be changed or supplemented by WikiMD. If you do not agree to the foregoing terms and conditions, you should not enter or use this site. See full disclaimer.
Credits:Most images are courtesy of Wikimedia commons, and templates Wikipedia, licensed under CC BY SA or similar.
Contributors: Prab R. Tumpati, MD
