Trisomy 22

From WikiMD's Wellness Encyclopedia

Trisomy 22 is a chromosome disorder in which an individual has an extra copy of chromosome 22. This condition is a type of aneuploidy and is often associated with miscarriage, stillbirth, and birth defects.

Causes[edit | edit source]

Trisomy 22 is caused by a mistake in cell division called nondisjunction. This error can occur in either the sperm or the egg before they combine to form an embryo. The resulting embryo has three copies of chromosome 22 instead of the usual two.

Symptoms[edit | edit source]

The symptoms of Trisomy 22 can vary widely, depending on how many cells have the extra chromosome and where those cells are in the body. Common symptoms include growth retardation, microcephaly (small head), hypertelorism (wide-set eyes), cleft palate, heart defects, and mental retardation.

Diagnosis[edit | edit source]

Trisomy 22 can be diagnosed before birth through prenatal testing. This can include amniocentesis or chorionic villus sampling (CVS). After birth, the condition can be diagnosed through a karyotype test, which examines the number and structure of a person's chromosomes.

Treatment[edit | edit source]

There is no cure for Trisomy 22. Treatment is focused on managing the symptoms and improving the quality of life for the individual. This can include physical therapy, occupational therapy, speech therapy, and special education services.

Prognosis[edit | edit source]

The prognosis for individuals with Trisomy 22 varies widely, depending on the severity of symptoms and the presence of other health conditions. Many individuals with Trisomy 22 have a shortened life expectancy due to the associated health problems.

See also[edit | edit source]

Trisomy 22 Resources
Wikipedia
WikiMD
Navigation: Wellness - Encyclopedia - Health topics - Disease Index‏‎ - Drugs - World Directory - Gray's Anatomy - Keto diet - Recipes

Search WikiMD

Ad.Tired of being Overweight? Try W8MD's physician weight loss program.
Semaglutide (Ozempic / Wegovy and Tirzepatide (Mounjaro / Zepbound) available.
Advertise on WikiMD

WikiMD's Wellness Encyclopedia

Let Food Be Thy Medicine
Medicine Thy Food - Hippocrates

Medical Disclaimer: WikiMD is not a substitute for professional medical advice. The information on WikiMD is provided as an information resource only, may be incorrect, outdated or misleading, and is not to be used or relied on for any diagnostic or treatment purposes. Please consult your health care provider before making any healthcare decisions or for guidance about a specific medical condition. WikiMD expressly disclaims responsibility, and shall have no liability, for any damages, loss, injury, or liability whatsoever suffered as a result of your reliance on the information contained in this site. By visiting this site you agree to the foregoing terms and conditions, which may from time to time be changed or supplemented by WikiMD. If you do not agree to the foregoing terms and conditions, you should not enter or use this site. See full disclaimer.
Credits:Most images are courtesy of Wikimedia commons, and templates Wikipedia, licensed under CC BY SA or similar.

Contributors: Prab R. Tumpati, MD