Tucker syndrome

A rare neurological disorder affecting the recurrent laryngeal nerve

Tucker Syndrome

Tucker syndrome is a rare neurological disorder characterized by dysfunction of the recurrent laryngeal nerve, which can lead to vocal cord paralysis and other associated symptoms. This condition is named after the physician who first described it.

Pathophysiology

The recurrent laryngeal nerve is a branch of the vagus nerve that supplies motor function and sensation to the larynx. In Tucker syndrome, this nerve is affected, leading to impaired movement of the vocal cords. The exact etiology of the nerve dysfunction in Tucker syndrome is not well understood, but it may involve genetic, autoimmune, or idiopathic factors.

Clinical Presentation

Patients with Tucker syndrome typically present with symptoms related to vocal cord paralysis, including:

• Hoarseness
• Dysphonia
• Dysphagia
• Stridor
• Dyspnea

The severity of symptoms can vary depending on the extent of nerve involvement and whether one or both vocal cords are affected.

Diagnosis

The diagnosis of Tucker syndrome is primarily clinical, based on the characteristic symptoms and the exclusion of other causes of recurrent laryngeal nerve palsy. Diagnostic tools may include:

• Laryngoscopy to visualize vocal cord movement
• Electromyography (EMG) to assess nerve function
• Imaging studies such as MRI or CT scan to rule out structural causes

Management

Treatment of Tucker syndrome focuses on managing symptoms and improving quality of life. Options may include:

• Voice therapy with a speech-language pathologist
• Surgical interventions such as medialization thyroplasty
• Use of botulinum toxin injections to reduce muscle spasms

Prognosis

The prognosis for individuals with Tucker syndrome varies. Some patients may experience spontaneous recovery of nerve function, while others may have persistent symptoms requiring ongoing management.

Related Pages

• Recurrent laryngeal nerve
• Vocal cord paralysis
• Vagus nerve

Images

Diagram of the recurrent laryngeal nerve