Benzbromarone

From WikiMD's Wellness Encyclopedia

(Redirected from Uricovac)

Benzbromarone

Medication used to treat gout


Benzbromarone is a medication used to treat gout and hyperuricemia. It is classified as a uricosuric agent, which means it helps to lower uric acid levels in the blood by increasing the excretion of uric acid in the urine.

Mechanism of Action[edit | edit source]

Benzbromarone works by inhibiting the reabsorption of uric acid in the kidneys, thereby increasing its excretion. This helps to reduce the levels of uric acid in the blood, which can prevent the formation of uric acid crystals that cause gout.

Uses[edit | edit source]

Benzbromarone is primarily used in the treatment of chronic gout and hyperuricemia. It is particularly useful in patients who are intolerant to other uricosuric agents or xanthine oxidase inhibitors like allopurinol.

Side Effects[edit | edit source]

Common side effects of benzbromarone include gastrointestinal disturbances, such as nausea and diarrhea. In rare cases, it can cause severe liver toxicity, which necessitates regular monitoring of liver function during treatment.

Contraindications[edit | edit source]

Benzbromarone is contraindicated in patients with severe liver disease, renal impairment, or those who are hypersensitive to the drug. It should also be used with caution in patients with a history of peptic ulcer disease.

History[edit | edit source]

Benzbromarone was first introduced in the 1970s. However, due to concerns about its potential to cause liver toxicity, it has been withdrawn from the market in several countries.

See Also[edit | edit source]

References[edit | edit source]


WikiMD
Navigation: Wellness - Encyclopedia - Health topics - Disease Index‏‎ - Drugs - World Directory - Gray's Anatomy - Keto diet - Recipes

Search WikiMD

Ad.Tired of being Overweight? Try W8MD's physician weight loss program.
Semaglutide (Ozempic / Wegovy and Tirzepatide (Mounjaro / Zepbound) available.
Advertise on WikiMD

WikiMD's Wellness Encyclopedia

Let Food Be Thy Medicine
Medicine Thy Food - Hippocrates

Medical Disclaimer: WikiMD is not a substitute for professional medical advice. The information on WikiMD is provided as an information resource only, may be incorrect, outdated or misleading, and is not to be used or relied on for any diagnostic or treatment purposes. Please consult your health care provider before making any healthcare decisions or for guidance about a specific medical condition. WikiMD expressly disclaims responsibility, and shall have no liability, for any damages, loss, injury, or liability whatsoever suffered as a result of your reliance on the information contained in this site. By visiting this site you agree to the foregoing terms and conditions, which may from time to time be changed or supplemented by WikiMD. If you do not agree to the foregoing terms and conditions, you should not enter or use this site. See full disclaimer.
Credits:Most images are courtesy of Wikimedia commons, and templates Wikipedia, licensed under CC BY SA or similar.

Contributors: Prab R. Tumpati, MD