Vindesine
Vindesine is a vinca alkaloid and a synthetic derivative of vinblastine. It is used in chemotherapy as a treatment for various types of cancer, including leukemia, lymphoma, melanoma, breast cancer, and lung cancer.
Pharmacology[edit | edit source]
Vindesine works by inhibiting microtubule dynamics, which are crucial for mitosis and cell division. This inhibition prevents the cancer cells from dividing and growing, leading to their death.
Side Effects[edit | edit source]
Like other chemotherapy drugs, vindesine can have several side effects. These can include nausea, vomiting, hair loss, and neutropenia, a condition characterized by low levels of neutrophils, a type of white blood cell.
History[edit | edit source]
Vindesine was first synthesized in the 1970s as a derivative of vinblastine. It was developed with the aim of reducing the side effects associated with vinblastine while maintaining its anti-cancer properties.
See Also[edit | edit source]
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