Vumon
Vumon is a brand name for the chemotherapy drug teniposide, which is used in the treatment of certain types of cancer. It is a type of drug known as a topoisomerase inhibitor, which works by preventing cancer cells from dividing and growing.
History[edit | edit source]
Vumon was first approved by the FDA in the United States in 1992. It was developed by the pharmaceutical company Bristol-Myers Squibb, and is also marketed under the generic name teniposide.
Uses[edit | edit source]
Vumon is used in the treatment of several types of cancer, including acute lymphoblastic leukemia (ALL), Hodgkin's lymphoma, and certain types of lung cancer. It is often used in combination with other chemotherapy drugs.
Mechanism of Action[edit | edit source]
Vumon works by inhibiting the action of an enzyme called topoisomerase II. This enzyme is necessary for DNA replication, and by inhibiting its action, Vumon prevents cancer cells from dividing and growing.
Side Effects[edit | edit source]
Like all chemotherapy drugs, Vumon can have serious side effects. These can include nausea, vomiting, hair loss, and a decrease in blood cells, which can lead to an increased risk of infection, bleeding, and anemia. More serious side effects can include allergic reactions and damage to the lungs.
See Also[edit | edit source]
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Contributors: Prab R. Tumpati, MD