ZNF593
ZNF593 is a protein that in humans is encoded by the ZNF593 gene. This protein is a member of the zinc finger protein family and has been identified as a tumor suppressor.
Function[edit | edit source]
ZNF593 is a nuclear protein that functions as a negative regulator of the cell cycle. It is believed to interact with the Opa interacting protein 5 (OIP5), which is a mitotic regulator. The interaction between ZNF593 and OIP5 is thought to play a role in the regulation of cell division and cell growth.
Clinical significance[edit | edit source]
Alterations in the ZNF593 gene have been associated with various types of cancer, including breast cancer, ovarian cancer, and lung cancer. The loss of ZNF593 function due to these alterations is believed to contribute to the development and progression of these cancers.
Research[edit | edit source]
Research into the function and clinical significance of ZNF593 is ongoing. Current research efforts are focused on understanding the precise role of ZNF593 in the cell cycle and how alterations in this gene contribute to cancer development.
See also[edit | edit source]
References[edit | edit source]
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Contributors: Prab R. Tumpati, MD