Mequitazine

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Mequitazine is a first-generation H1 receptor antagonist that is used in the treatment of allergic conditions such as hay fever, urticaria, and asthma. It is marketed under various brand names including Primalan.

Pharmacology[edit | edit source]

Mequitazine works by blocking the action of histamine, a substance in the body that causes allergic symptoms. It is a competitive antagonist at the H1 receptor, which means it prevents histamine from binding to this receptor and triggering an allergic response.

Uses[edit | edit source]

Mequitazine is used to relieve symptoms of allergic conditions such as hay fever, urticaria, and asthma. These symptoms can include sneezing, runny nose, itchy eyes, and wheezing. It can also be used to treat insomnia due to its sedative effects.

Side Effects[edit | edit source]

Common side effects of mequitazine include drowsiness, dizziness, dry mouth, and blurred vision. Less common side effects can include nausea, headache, and palpitations. In rare cases, it can cause seizures or hallucinations.

Contraindications[edit | edit source]

Mequitazine should not be used in people with a known hypersensitivity to the drug or any of its components. It should also be used with caution in people with glaucoma, prostate problems, or urinary retention.

Interactions[edit | edit source]

Mequitazine can interact with other medications, including other antihistamines, sedatives, tranquilizers, and alcohol. These interactions can increase the sedative effects of mequitazine.

Dosage[edit | edit source]

The dosage of mequitazine will depend on the individual and the condition being treated. It is usually taken once or twice a day.

See Also[edit | edit source]

Mequitazine Resources
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Contributors: Prab R. Tumpati, MD