From WikiMD's Food, Medicine & Wellness Encyclopedia

1,3-Benzodioxolyl-N-methylpentanamine, also known as MDPV, is a psychoactive drug that has stimulant properties. MDPV is part of the chemical compounds known as synthetic cathinones, which are a category of drugs related to the naturally occurring khat plant. It has gained notoriety as a component of so-called "bath salts", which are illegal recreational drugs that mimic the effects of other stimulants such as amphetamine and cocaine.

Chemistry[edit | edit source]

1,3-Benzodioxolyl-N-methylpentanamine is a derivative of pyrovalerone, featuring a phenethylamine core with an alkyl group attached at the alpha carbon, and a ketone at the beta carbon. It also has a methylenedioxy group attached to the phenyl ring. This chemical structure is responsible for its pharmacological properties and its ability to act as a norepinephrine-dopamine reuptake inhibitor (NDRI), which increases the concentrations of the neurotransmitters norepinephrine and dopamine in the brain, leading to stimulant effects.

Effects[edit | edit source]

The effects of 1,3-Benzodioxolyl-N-methylpentanamine can include euphoria, increased alertness, and increased energy. However, it can also lead to negative effects such as anxiety, paranoia, and hallucinations. The drug can cause significant harm when abused, including potential for addiction, neurotoxicity, and various cardiovascular problems.

Legal Status[edit | edit source]

The legal status of 1,3-Benzodioxolyl-N-methylpentanamine varies by country, but it has been made illegal in many jurisdictions due to its potential for abuse and harm. In some places, it is classified as a controlled substance under the same regulations as other harmful stimulants.

Health Risks[edit | edit source]

The health risks associated with the use of 1,3-Benzodioxolyl-N-methylpentanamine are significant. They can include psychosis, severe dehydration, hyperthermia, and even death. The risk of addiction and the potential for long-term psychological and physical harm make it a substance of concern for public health authorities.

Conclusion[edit | edit source]

1,3-Benzodioxolyl-N-methylpentanamine is a powerful psychoactive substance with a high potential for abuse and significant health risks. Its status as an illegal or controlled substance in many parts of the world reflects the concerns about its safety and the potential for harm.


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Contributors: Prab R. Tumpati, MD