17α-Ethynyl-3α-androstanediol

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17α-Ethynyl-3α-androstanediol is a synthetic androgen and anabolic steroid (AAS) that is derived from dihydrotestosterone (DHT). It is a potent androgen receptor agonist and has been studied for its potential use in various medical applications.

Chemical Structure

17α-Ethynyl-3α-androstanediol is a derivative of androstanediol, which is itself a metabolite of dihydrotestosterone. The chemical structure of 17α-Ethynyl-3α-androstanediol includes an ethynyl group at the 17α position and hydroxyl groups at the 3α and 17β positions.

Pharmacology

As an androgen receptor agonist, 17α-Ethynyl-3α-androstanediol binds to and activates the androgen receptor, leading to the expression of androgen-responsive genes. This results in the development and maintenance of male secondary sexual characteristics and anabolic effects such as increased muscle mass and strength.

Medical Uses

While 17α-Ethynyl-3α-androstanediol has been studied for its potential therapeutic applications, it is not currently approved for medical use. Research has explored its potential in treating conditions such as hypogonadism, muscle wasting, and certain types of breast cancer.

Side Effects

The side effects of 17α-Ethynyl-3α-androstanediol are similar to those of other androgens and anabolic steroids. These may include acne, hirsutism, voice deepening, and liver toxicity. Long-term use can lead to more serious health issues such as cardiovascular disease and endocrine disruption.

Legal Status

The legal status of 17α-Ethynyl-3α-androstanediol varies by country. In many places, it is classified as a controlled substance due to its potential for abuse and adverse health effects.

See Also

• Androgen
• Anabolic steroid
• Dihydrotestosterone
• Androgen receptor
• Hypogonadism
• Muscle wasting
• Breast cancer

External Links

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